Premature ovarian insufficiency (POI) is one of the most emotionally difficult fertility diagnoses a woman can receive. A condition where the ovaries stop functioning normally before the age of 40, POI affects roughly 1 in 100 women and often feels like a door slamming shut on the dream of having children. But at Hanabusa IVF in San Diego, Dr. Lyndon Chang and Dr. Diana LeBlanc work with POI patients every day — and they bring both expertise and hope to the conversation.
What makes Hanabusa IVF uniquely positioned to help women with POI is their specialization in complex fertility cases. While standard IVF clinics may refer POI patients directly to donor egg programs, the team at Hanabusa first explores whether a woman may still have viable follicles that could be stimulated or naturally selected. This includes natural cycle monitoring over multiple months, ovarian rejuvenation with PRP, and ultra-gentle mini-stimulation protocols.
Dr. Diana LeBlanc has spoken about the importance of not giving up prematurely on a woman's own eggs. The clinic's guiding philosophy — "one size doesn't fit all" — is perhaps most meaningfully applied to POI patients, where personalized timing, hormonal support, and laboratory expertise can sometimes yield surprising results.
Hanabusa IVF's laboratory is directed by Lisa Nelson, who brings over a decade of specialized vitrification experience as the dedicated lab partner for the Asian Egg Bank. This precision in freezing and thawing eggs and embryos is critical for POI patients, where cumulative banking across multiple cycles may be the best strategy.
For POI patients who ultimately need donor eggs, Hanabusa IVF also runs a comprehensive Donor Egg Program with access to a broad donor network including diverse ethnic backgrounds — particularly relevant for the clinic's international patient base across Asia, Australia, and Canada.
If you or someone you love has received a POI diagnosis, Hanabusa IVF invites you to schedule a personalized consultation. The clinic is located at 4910 Directors Place, Suite 150, San Diego, CA 92121. Call (858) 480-5400 or visit hanabusaivf.com to take the first step.